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Novel Phenotypes (WP3)

WP3 will ensure that we move beyond classical disease and trait phenotypes by providing expertise and resources in two areas. The first relates to improved analysis for multivariate and longitudinal phenotypes, the second to the provision of genomic data (expression profiling initially, proteomics and metabonomics after) to facilitate ‘genetical genomics’ relating DNA sequence variation, intermediate genomic phenotypes and disease/trait phenotypes. WP3 will interact with WP1 & WP6.


The ENGAGE project consists of 8 research lines and 2 components dealing with “Training and Dissemination” and “Coordination”. Each component forms a workpackage (WP).


WP1 - Genome wide data integration and statistical genetics

WP2 - Novel sources of genome-wide variation

WP3 - Novel phenotypes

WP4 - Informatics and bioinformatics

WP5 - Identifying the causal variants

WP6 - Epidemiology and joint effects

WP7 - Clinical translation

WP8 - Societal aspects

WP9 - Dissemination and Training

WP10 Coordination