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Novel Sources of Genomewide Variation (WP2)

 WP2 will be responsible for ensuring that ENGAGE exploits the potential of accessing additional types of GWA (structural variants; methylation variants; deep resequencing) as the relevant technologies mature. ENGAGE Partners provide expertise and resources to expedite appropriate application of these technologies to ENGAGE samples. WP2 will have some resources to initiate specific small-scale projects in each area, though application to large sample sets will be reliant on external funding. WP2 will liaise closely with WP1 and WP4 to ensure that data are made available to the WP1 in standardized format and with relevant meta-data.

WORK PACKAGES

The ENGAGE project consists of 8 research lines and 2 components dealing with “Training and Dissemination” and “Coordination”. Each component forms a workpackage (WP).

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WP1 - Genome wide data integration and statistical genetics

WP2 - Novel sources of genome-wide variation

WP3 - Novel phenotypes

WP4 - Informatics and bioinformatics

WP5 - Identifying the causal variants

WP6 - Epidemiology and joint effects

WP7 - Clinical translation

WP8 - Societal aspects

WP9 - Dissemination and Training

WP10 Coordination